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Sunday, April 19, 2009

Morphologic and Functional Imaging of Malignant Pleural Mesothelioma

Pleural malignant mesothelioma (MPM) Agresif is a tumor arising from the pleura and frequently extends to adjacent structures. MPM cells produce and respond to many angiogenic factors, such as vascular endothelial growth factor (VEGF). VEGF Expression in MPM is correlated with microvascular density, which is associated with poor life. CT has been used as the basic imaging modality for clinical evaluation of MPM. Main findings include nodular pleural thickening, unilateral pleural fluid, and tumor invasion of adjacent structures. CT tends to underestimate early chest wall invasion and peritoneal involvement and has known limitations in the evaluation node metastases Getah cornea. Perfusion CT can evaluate the microvasculature of Tumors, temporary shortages, such as high or Radiasi exposed side effects of iodinated contrast, limit their use in both research and clinical settings. MRI can provide additional information to CT. Because the very contrast resolution, MRI is superior to CT, the difference in a very Subur of pleural disease, and assessment in the chest wall and diaphragm involvement Samaritan. Perfusion MRI is the most promising technique for assessment of tumor microvasculature. In MPM, many effects of chemotherapy can be monitored with perfusion MRI. Have shown that FDG-PET is useful for the differences from the Subur Luka severe, to metabolic staging and monitoring response to Terapi MPM, and that have prognostic value. A report early PET / CT imaging of MPM has shown increased accuracy of overall staging, improving the assessment of tumor resectability. PET / CT appears to be superior over other imaging modalities in detecting broad involvement of the disease, and identify hidden unsuspected distant metastases.

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